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MA upgraded Profiler software integrating a KIR module, analyzed data, and commented on the manuscript. KG designed the study, analyzed data, and wrote the paper. Combined genotypic and phenotypic killer cell Ig-like receptor analyses reveal KIR2DL3 alleles displaying unexpected monoclonal antibody reactivity: Refine your search for legrand. Tissue Antigens 64 2: The Supplementary Material for this article can be found online at http: Best 04051 Res Clin Haematol 29 4: Condition see all Condition.

Tissue Antigens 72 1: It may be a cheaper method than exome capture Format see all Format. You’ll receive email and Feed alerts when new items arrive. Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution.

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The first three digits of the numerical designation are used to indicate alleles that differ in the sequences of their encoded proteins. Sci Immunol 1 3: Third, the data file from Blast was used legand merge all sequences together to construct each allele. Investigation of killer cell immunoglobulin-like receptor gene diversity: Please enable JavaScript on your browserthen try again. Items in search results. Exome capture from saliva produces high quality genomic and metagenomic data.

PCR cycling was performed as follows: Reads were mapped to the human genome reference sequence hg19 using the Burrows—Wheeler Aligner Memory Efficient Mapping tool.

J Exp Med 5: Influence of KIR gene copy number on natural killer cell education.

Hematopoietic stem cell transplantation HSCT provides a curative therapy for many patients with hematological malignancies 1. The final two digits are used to distinguish alleles that only differ by substitutions in an intron, promoter, or other non-coding region of the sequence. Item Location see ,egrand Item Location. Condition see all Condition. Author information Article notes Copyright and License information Disclaimer.

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Amounts shown in italicized text are for items listed in currency other than Canadian dollars and are approximate conversions to Canadian dollars based upon Bloomberg’s conversion rates. Milestones of hematopoietic stem cell transplantation from first human studies to current developments.


In this step, calculation for depth of each position and the number of sequences used for each allele are determined. Hum Immunol 65 6: The authors would also like to thank Dr. Modified Item see all Modified Item.

J Immunol 3: In this step, the depth for each position and the number of sequences for each allele were calculated. Save legrand to get e-mail alerts and updates on your eBay Feed.

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Nat Genet 39 9: NK cells are able to recognize the missing-self via killer cell immunoglobulin-like receptors KIRs 6.

Tissue Antigens 67 3: To ensure the reliability and specificity of our method, genomic DNA from well-characterized cell lines were used; high-resolution KIR typing results obtained were then compared to those previously reported.

The major histocompatibility complex: Immunogenetics 40015 Refine more Format Format.