INFeD® improved the hemoglobin response to erythropoietic therapy in patients with documented INFeD® full Prescribing Information. Watson Pharma, Inc. 1 mL of INFeD provides 50 mg of elemental iron UpToDate (courtesy of Lexicomp), or the prescribing information. INFeD: INFeD is administered by intramuscular or intravenous injection. Before . during the acute phase of infectious renal disease (manufacturer’s information) . Therefore, the therapeutic prescription use of iron is usually compatible with.
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Following intramuscular injection of iron dextran, the drug is slowly absorbed in two stages primarily through the lymphatic system. Specific guidelines for dosage adjustments in hepatic impairment are invormation available. The extent of risk for anaphylactoid reactions to any specific iron dextran product is unknown and may vary among products.
Iron dextran (INFeD) | – A Hematology Oncology Wiki
Parenteral iron supplement of ferric oxyhydroxide complexed with dextrans; rapidly repletes iron stores in deficiency from anemia or blood loss; sometimes associated with severe hypersensitivity.
If a breast-feeding infant experiences an adverse effect related to a maternally ingested drug, healthcare providers are encouraged to report the adverse effect to the FDA.
Instructions for test dose administration for all indications. Ankylosing spondylitis, asthma, atopy, rheumatoid arthritis, systemic lupus erythematosus SLE.
Major Parenteral iron formulas are generally only indicated for use in patients with documented iron deficiency in whom oral administration is either impossible or unsatisfactory.
Too much iron can be toxic, and iron is not easily eliminated from the body. There are limits to the volume of iron dextran that may be injected IV undiluted per 24 hours based on patient age and weight; see dosage guidelines. If test dose uneventful, give the remainder of the total dose as 50 mg of elemental iron per day IM or slow IV until the total calculated dose is given.
To avoid staining of subcutaneous tissue, use the Z-track technique of injection. Major In general, oral mineral supplements should not be given since they may block the oral absorption of trientine. Therefore, the therapeutic prescription use of iron is usually compatible with breast-feeding if the lactating mother needs treatment for iron deficiency.
Infants 4 months and older weighing less than 5 kg. Adult men, Adolescent males, and Postmenopausal women. Facilities for cardiopulmonary resuscitation and personnel trained in the detection and treatment of anaphylactoid reactions must be available during administration.
Cardiac disease, hypotension, intravenous administration. Do not administer iron during dimercaprol treatment. A test dose should be given prior to administration of the initial therapeutic dose.
Give INFeD test doses gradually over at presctibing 30 seconds. Uptake by these cells occurs at a rate of about 10—20 mg per hour. INFeD is administered by intramuscular or intravenous injection. Parenteral iron preparations e. Before administering therapeutic doses, a test dose of 25 mg 0.
Normal erythropoiesis is dependent on the concentration of iron and erythropoietin available in the plasma. Patients with informatkon cardiac disease may have exacerbation of cardiovascular symptoms if adverse effects occur following iron dextran administration. In general, iron supplementation should not begin in premature infants until adequate vitamin E is supplied in the diet; human breast milk and modern infant formulas usually supply adequate dietary vitamin E.
If test dose uneventful, infuse the remainder of the total calculated dose see equation IV over 2 to 6 hours. Each 1 mL of inforrmation dextran injection contains 50 mg of elemental iron.
Iron dextran (INFeD)
Both animal and human data indicate that the bulk of intravenous iron is sequestered in the reticuloendothelial system i. Send the page ” ” to a friend, relative, colleague or yourself.
Most patients with chronic kidney disease will require supplemental iron e. Evaluate transferrin saturation and serum ferritin before and during epoetin alfa treatment. Iron dextran should be administered to pregnant women only if the benefits outweigh the potential risks to the fetus. If test dose uneventful, give the remainder of the total dose as 50 mg of iron dextran per day IM or slow IV until the total calculated dose is given.
The following are generally accepted limits in the treatment of iron-deficient patients. Give DexFerrum test doses gradually over at least 5 minutes.
Infants and Children 4 months and informstion weighing 5 to 9. Once taken into reticuloendothelial cells, the iron from the iron dextran complex is separated and added to the body’s total iron stores. While iron is excreted into breast-milk, the iron content of breast milk is not readily affected by the iron content of the maternal diet or inforrmation maternal serum iron level.
Iron dextran is contraindicated for use in patients with anemia not associated with iron deficiency.