ALOPECIA MUCINOSA PDF

Follicular mucinosis is a term that encompasses three related entities. Alopecia mucinosa, Urticaria-like follicular mucinosis, and cutaneous lymphoma related. On hair-bearing skin (e.g. scalp), overlying alopecia is notable, hence the term “ alopecia mucinosa” (see Figure 5). Plaques are often composed of densely. Alopecia mucinosa is a skin disorder that generally presents, but not exclusively, as erythematous plaques or flat patches without hair primarily on the scalp.

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Caution if used in patients with gastritis, peptic ulcer disease, or renal insufficiency. On hair-bearing skin e.

Considering the rapid and complete response to antileprosy treatment in 7 cases of Alopecia mucinosa three cases described in this paper and the four similar cases described earlier[ 10 ]it is most unlikely that the response was a natural remission of the disease.

Discussion The objective of this paper is to draw attention to an unusual finding, that is, rapid and complete response of Alopecia mucinosa to antileprosy treatment with no subsequent relapse over fairly long periods of posttreatment observation. And are there other choices?

Alopecia mucinosa – Wikipedia

Images hosted on other servers: Our cases too, would aloepcia been accepted as leprosy if a biopsy had not been performed as there was clinical suspicion of leprosy and all of them did rapidly and completely respond to antileprosy treatment. Vanessa Ngan, Staff Writer, You can help Wikipedia by expanding it. Idiopathic follicular mucinosis on the trunk. If associated with an underlying neoplastic or inflammatory disorder, treatment of the associated disease is warranted.

Three cases with single lesion of Alopecia mucinosa follicular mucinosis were treated with antileprosy treatment and showed rapid and complete resolution of the lesions with no recurrence on extended follow-up. Discontinue therapy or consider slow titration over months or years after complete response is alopeciw. The upper and mid dermis had a moderately dense perivascular lymphocytic infiltrate with few eosinophils.

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Alopecia mucinosa

This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment.

This article has been cited by other articles in PMC. Nil Conflict of Interest: The biopsy showed a moderately dense superficial and mudinosa perivascular infiltrate of lymphocytes with occasional eosinophils without any granulomas in the alopecka.

Case 2 A year-old girl presented in Marchwith hair loss over left eyebrow and dry hypopigmented skin of adjacent forehead.

Home About Us Advertise Amazon. Histogenesis of mucin in follicular mucinosis.

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Avoid use ,ucinosa patients under age 8. With the results of the biopsy, however, these cases would be diagnosed as Alopecia mucinosa! Case Reports Case 1 A year-old boy presented in Septemberwith a hypopigmented and hypoaesthetic shiny patch on the left cheek of few months duration. Subsequently the lesion was seen to have completely cleared at follow up at the end of 1 and 2 years. Therapeutic options and efficacy are based on retrospective case series or anecdotal reports; no controlled trials exist.

A year-old boy presented in Septemberwith a hypopigmented and hypoaesthetic shiny patch on the left cheek of few months duration. A clinical diagnosis of leprosy was considered and a 3 mm punch biopsy sample revealed features of follicular mucinosis with most follicles in the sections showing spaces between keratinocytes containing wisps of bluish mucin.

No reliable distinguishing clinical, histological, or molecular parameter exists. Abstract Three cases with single lesion of Alopecia mucinosa follicular mucinosis were treated with antileprosy treatment and showed rapid and complete resolution of the lesions with no recurrence on extended follow-up.

Immunohistochemistry showed the infiltrating lymphocytes to be CD3 and CD4 positive. Suggested therapies are muciosa on anecdotal reports or small case series.

Lever’s Histopathology of the skin. Alopecia mucinosa has been divided into the primary or idiopathic variety and the secondary type associated with cutaneous T cell lymphoma. Therapy should be tailored to the individual patient, with consideration given to the extent of involvement lesion location, size, number. The skin lesion and hair loss had been present for about 3 months and was gradually progressive.

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In sum, we present three cases of Alopecia mucinosa, who presented with single lesions on the face, had follicular mucinosis on biopsy and who healed rapidly and completely with initiation of antileprosy treatment. Paronychia Acute Chronic Chevron nail Congenital onychodysplasia of the index fingers Green nails Half and half nails Hangnail Hapalonychia Hook nail Ingrown nail Lichen planus of the nails Longitudinal erythronychia Malalignment of the nail plate Median nail dystrophy Mees’ lines Melanonychia Muehrcke’s lines Nail—patella syndrome Onychoatrophy Onycholysis Onychomadesis Onychomatricoma Onychomycosis Onychophosis Onychoptosis defluvium Onychorrhexis Onychoschizia Platonychia Pincer nails Plummer’s nail Psoriatic nails Pterygium inversum unguis Pterygium unguis Purpura of the nail bed Racquet nail Red lunulae Shell nail syndrome Splinter hemorrhage Spotted lunulae Staining of the nail plate Stippled nails Subungual hematoma Terry’s nails Twenty-nail dystrophy.

Hirsutism Acquired localised generalised patterned Congenital generalised localised X-linked Prepubertal. Follicular infundibulum keratinocytes and outer root sheath are separated by pools of mucin Mixed infiltrate of lymphocytes, histiocytes and conspicuous eosinophils Marked follicular dilation with cyst formation and perifollicular scarring Both the dermis and and affected epithelium are typically infiltrated by lymphocytes, histiocytes and eosinophils In cases associated with lymphoma, atypical lymphocytes, convoluted lymphocytes, large transformed cells and mitotic figures may be seen.

This page was last edited on 21 Juneat The authors suggest that in regions endemic for leprosy, such as India, single lesion Alopecia mucinosa on the face in children and young adults should be given antileprosy treatment.